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The Actions and Mechanisms of P2X7R and p38 MAPK Activation in Mediating Bortezomib-Induced Neuropathic Pain

The proteasome inhibitor bortezomib (BTZ) is a potent first-line anticancer drug for multiple myeloma; nonetheless, it induced peripheral neuropathy. It has been suggested that many cytokines may play a role in mediating neuropathic pain, but the underlying molecular mechanism is not fully understoo...

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Detalles Bibliográficos
Autores principales:	Guo, Yan, Xu, Xiaobo, Huang, Jingyi, Wang, Zhen, Li, Zhenzhong, Liu, Zhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376423/ https://www.ncbi.nlm.nih.gov/pubmed/32733956 http://dx.doi.org/10.1155/2020/8143754

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