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Glutamatergic and GABAergic reactivity and cognition in 22q11.2 deletion syndrome and healthy volunteers: A randomized double-blind 7-Tesla pharmacological MRS study

AIMS: 22q11.2 deletion syndrome (22q11.2DS) is associated with impaired cognitive functioning. Glutamatergic pathways have been linked with cognition and are hypothesized to be disrupted in 22q11.2DS patients, possibly ‘shifting’ the excitatory (glutamate)/inhibitory (GABA) balance. Hence, the gluta...

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Detalles Bibliográficos
Autores principales: Vingerhoets, Claudia, Tse, Desmond HY, van Oudenaren, Mathilde, Hernaus, Dennis, van Duin, Esther, Zinkstok, Janneke, Ramaekers, Johannes G, Jansen, Jacobus FA, McAlonan, Grainne, van Amelsvoort, Therese
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376622/
https://www.ncbi.nlm.nih.gov/pubmed/32448020
http://dx.doi.org/10.1177/0269881120922977