In vitro and in vivo human metabolism and pharmacokinetics of S‐ and R‐praziquantel

Racemic praziquantel (PZQ) is the drug of choice for the treatment of schistosomiasis. R‐Praziquantel (R‐PZQ) has been shown as the therapeutic form, whereas S‐PZQ is less efficacious and responsible for the bitter taste of the tablet. This study aimed at investigating the metabolism of R‐ and S‐PZQ...

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Detalles Bibliográficos
Autores principales: Kapungu, Nyasha Nicole, Li, Xueqing, Nhachi, Charles, Masimirembwa, Collen, Thelingwani, Roslyn Stella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376644/
https://www.ncbi.nlm.nih.gov/pubmed/32700798
http://dx.doi.org/10.1002/prp2.618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376644/
https://www.ncbi.nlm.nih.gov/pubmed/32700798
http://dx.doi.org/10.1002/prp2.618

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