A novel coordination complex of platinum (PT) induces cell death in colorectal cancer by altering redox balance and modulating MAPK pathway

BACKGROUND: Colorectal cancer (CRC) is a heterogeneous tumor having various genetic alterations. The current treatment options had limited impact on disease free survival due to therapeutic resistance. Novel anticancer agents are needed to treat CRC specifically metastatic colorectal cancer. A novel...

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Detalles Bibliográficos
Autores principales: Al-Khayal, Khayal, Vaali-Mohammed, Mansoor-Ali, Elwatidy, Mohammed, Bin Traiki, Thamer, Al-Obeed, Omar, Azam, Mohammad, Khan, Zahid, Abdulla, Maha, Ahmad, Rehan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376665/
https://www.ncbi.nlm.nih.gov/pubmed/32703189
http://dx.doi.org/10.1186/s12885-020-07165-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376665/
https://www.ncbi.nlm.nih.gov/pubmed/32703189
http://dx.doi.org/10.1186/s12885-020-07165-w

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