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Apoptosis triggers the release of microRNA miR-294 in spent culture media of blastocysts

PURPOSE: To study whether members of the miR-290-295 cluster in spent culture medium (SCM) of embryos are correlated with morphokinetics and apoptosis. METHODS: Cryopreserved 1-cell stage mouse embryos were cultured to the blastocyst stage, development was monitored by time-lapse, 59 SCM were collec...

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Detalles Bibliográficos
Autores principales: Makri, Dimitra, Efstathiou, Panagiota, Michailidou, Eftychia, Maalouf, Walid E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376808/
https://www.ncbi.nlm.nih.gov/pubmed/32440932
http://dx.doi.org/10.1007/s10815-020-01796-5