Descriptive Proteome Analysis to Investigate Context-Dependent Treatment Responses to OXPHOS Inhibition in Colon Carcinoma Cells Grown as Monolayer and Multicellular Tumor Spheroids

[Image: see text] We have previously identified selective upregulation of the mevalonate pathway genes upon inhibition of oxidative phosphorylation (OXPHOS) in quiescent cancer cells. Using mass spectrometry-based proteomics, we here investigated whether these responses are corroborated on the prote...

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Detalles Bibliográficos
Autores principales: Steinmetz, Julia, Senkowski, Wojciech, Lengqvist, Johan, Rubin, Jenny, Ossipova, Elena, Herman, Stephanie, Larsson, Rolf, Jakobsson, Per-Johan, Fryknäs, Mårten, Kultima, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376893/
https://www.ncbi.nlm.nih.gov/pubmed/32715210
http://dx.doi.org/10.1021/acsomega.0c01419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376893/
https://www.ncbi.nlm.nih.gov/pubmed/32715210
http://dx.doi.org/10.1021/acsomega.0c01419

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