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Differential expression of receptors mediating receptor-mediated transcytosis (RMT) in brain microvessels, brain parenchyma and peripheral tissues of the mouse and the human

Receptor-mediated transcytosis (RMT) is a principal pathway for transport of macromolecules essential for brain function across the blood–brain barrier (BBB). Antibodies or peptide ligands which bind RMT receptors are often co-opted for brain delivery of biotherapeutics. Constitutively recycling tra...

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Detalles Bibliográficos
Autores principales: Zhang, Wandong, Liu, Qing Yan, Haqqani, Arsalan S., Leclerc, Sonia, Liu, Ziying, Fauteux, François, Baumann, Ewa, Delaney, Christie E., Ly, Dao, Star, Alexandra T., Brunette, Eric, Sodja, Caroline, Hewitt, Melissa, Sandhu, Jagdeep K., Stanimirovic, Danica B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376922/
https://www.ncbi.nlm.nih.gov/pubmed/32698806
http://dx.doi.org/10.1186/s12987-020-00209-0