Psoralen alleviates high glucose-induced HK-2 cell injury by inhibition of Smad 2 signaling via upregulation of microRNA 874

BACKGROUND: Diabetic nephropathy (DN) causes the vast proportion of excess mortality for patients with diabetes. Novel therapeutic approaches slowing down its incidence is still lacking. Psoralen is the major active ingredient of Psoralea corylifolia Linn. (PCL), which was used to treat a number of...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Yongtao, Zhong, Lili, Li, Hailun, Xu, Yong, Li, Xiang, Zheng, Donghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376944/
https://www.ncbi.nlm.nih.gov/pubmed/32698907
http://dx.doi.org/10.1186/s40360-020-00434-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376944/
https://www.ncbi.nlm.nih.gov/pubmed/32698907
http://dx.doi.org/10.1186/s40360-020-00434-1

Ejemplares similares