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Psoralen alleviates high glucose-induced HK-2 cell injury by inhibition of Smad 2 signaling via upregulation of microRNA 874
BACKGROUND: Diabetic nephropathy (DN) causes the vast proportion of excess mortality for patients with diabetes. Novel therapeutic approaches slowing down its incidence is still lacking. Psoralen is the major active ingredient of Psoralea corylifolia Linn. (PCL), which was used to treat a number of...
Autores principales: | Lin, Yongtao, Zhong, Lili, Li, Hailun, Xu, Yong, Li, Xiang, Zheng, Donghui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376944/ https://www.ncbi.nlm.nih.gov/pubmed/32698907 http://dx.doi.org/10.1186/s40360-020-00434-1 |
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