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Integrated epigenetic biomarkers in circulating cell-free DNA as a robust classifier for pancreatic cancer

BACKGROUND: The high lethal rate of pancreatic cancer is partly due to a lack of efficient biomarkers for screening and early diagnosis. We attempted to develop effective and noninvasive methods using 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) markers from circulating cell-free DNA (c...

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Detalles Bibliográficos
Autores principales: Cao, Feng, Wei, Ailin, Hu, Xinlei, He, Yijing, Zhang, Jun, Xia, Lin, Tu, Kailing, Yuan, Jue, Guo, Ziheng, Liu, Hongying, Xie, Dan, Li, Ang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376965/
https://www.ncbi.nlm.nih.gov/pubmed/32703318
http://dx.doi.org/10.1186/s13148-020-00898-2