PD-L1 expression increased by IFN-γ via JAK2-STAT1 signaling and predicts a poor survival in colorectal cancer

PD-L1 inhibitors are widely used in tumor immunotherapy, but their mechanism in colorectal cancer remains unclear. The present study aimed to investigate the mechanisms underlying programmed death ligand 1 (PD-L1) regulation via the interferon-γ (IFN-γ)/janus kinase (JAK)/STAT signaling pathway, and...

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Detalles Bibliográficos
Autores principales: Zhao, Tiancheng, Li, Yezhou, Zhang, Jiayu, Zhang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377091/
https://www.ncbi.nlm.nih.gov/pubmed/32724352
http://dx.doi.org/10.3892/ol.2020.11647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377091/
https://www.ncbi.nlm.nih.gov/pubmed/32724352
http://dx.doi.org/10.3892/ol.2020.11647

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