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PD-L1 expression increased by IFN-γ via JAK2-STAT1 signaling and predicts a poor survival in colorectal cancer

PD-L1 inhibitors are widely used in tumor immunotherapy, but their mechanism in colorectal cancer remains unclear. The present study aimed to investigate the mechanisms underlying programmed death ligand 1 (PD-L1) regulation via the interferon-γ (IFN-γ)/janus kinase (JAK)/STAT signaling pathway, and...

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Detalles Bibliográficos
Autores principales:	Zhao, Tiancheng, Li, Yezhou, Zhang, Jiayu, Zhang, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377091/ https://www.ncbi.nlm.nih.gov/pubmed/32724352 http://dx.doi.org/10.3892/ol.2020.11647

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