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Drug targeting CYP2E1 for the treatment of early-stage alcoholic steatohepatitis

BACKGROUND AND AIMS: Alcoholic steatohepatitis (ASH)—the inflammation of fatty liver—is caused by chronic alcohol consumption and represents one of the leading chronic liver diseases in Western Countries. ASH can lead to organ dysfunction or progress to hepatocellular carcinoma (HCC). Long-term alco...

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Detalles Bibliográficos
Autores principales: Diesinger, Torsten, Buko, Vyacheslav, Lautwein, Alfred, Dvorsky, Radovan, Belonovskaya, Elena, Lukivskaya, Oksana, Naruta, Elena, Kirko, Siarhei, Andreev, Viktor, Buckert, Dominik, Bergler, Sebastian, Renz, Christian, Schneider, Edith, Kuchenbauer, Florian, Kumar, Mukesh, Günes, Cagatay, Büchele, Berthold, Simmet, Thomas, Müller-Enoch, Dieter, Wirth, Thomas, Haehner, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377376/
https://www.ncbi.nlm.nih.gov/pubmed/32701948
http://dx.doi.org/10.1371/journal.pone.0235990