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Bleaching correction for DNA measurements in highly diluted solutions using confocal microscopy
Determining the concentration of nucleic acids in biological samples precisely and reliably still is a challenge. In particular when only very small sample quantities are available for analysis, the established fluorescence-based methods give insufficient results. Photobleaching is seen as the main...
Autores principales: | Sparrenberg, Lorenz Tim, Greiner, Benjamin, Mathis, Harald Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377397/ https://www.ncbi.nlm.nih.gov/pubmed/32702012 http://dx.doi.org/10.1371/journal.pone.0231918 |
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