Family-based exome sequencing combined with linkage analyses identifies rare susceptibility variants of MUC4 for gastric cancer

Genome-wide association studies of gastric cancer (GC) cases have revealed common gastric cancer susceptibility loci with low effect size. We investigated rare variants with high effect size via whole-exome sequencing (WES) of subjects with familial clustering of gastric cancer. WES of DNAs from the...

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Detalles Bibliográficos
Autores principales: Choi, Yoon Jin, Ohn, Jung Hun, Kim, Nayoung, Kim, Wonji, Park, Kyungtaek, Won, Sungho, Sael, Lee, Shin, Cheol Min, Lee, Sun Min, Lee, Sejoon, An, Hyun Joo, Jang, Dong Man, Han, Byung Woo, Lee, Hye Seung, Kang, Seung Joo, Kim, Joo Sung, Lee, Dong Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377420/
https://www.ncbi.nlm.nih.gov/pubmed/32701958
http://dx.doi.org/10.1371/journal.pone.0236197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377420/
https://www.ncbi.nlm.nih.gov/pubmed/32701958
http://dx.doi.org/10.1371/journal.pone.0236197

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