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Mycobacterium marinum phthiocerol dimycocerosates enhance macrophage phagosomal permeabilization and membrane damage

Phthiocerol dimycocerosates (PDIMs) are a class of mycobacterial lipids that promote virulence in Mycobacterium tuberculosis and Mycobacterium marinum. It has recently been shown that PDIMs work in concert with the M. tuberculosis Type VII secretion system ESX-1 to permeabilize the phagosomal membra...

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Detalles Bibliográficos
Autores principales: Osman, Morwan M., Pagán, Antonio J., Shanahan, Jonathan K., Ramakrishnan, Lalita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377490/
https://www.ncbi.nlm.nih.gov/pubmed/32701962
http://dx.doi.org/10.1371/journal.pone.0233252