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Mycobacterium marinum phthiocerol dimycocerosates enhance macrophage phagosomal permeabilization and membrane damage
Phthiocerol dimycocerosates (PDIMs) are a class of mycobacterial lipids that promote virulence in Mycobacterium tuberculosis and Mycobacterium marinum. It has recently been shown that PDIMs work in concert with the M. tuberculosis Type VII secretion system ESX-1 to permeabilize the phagosomal membra...
Autores principales: | Osman, Morwan M., Pagán, Antonio J., Shanahan, Jonathan K., Ramakrishnan, Lalita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377490/ https://www.ncbi.nlm.nih.gov/pubmed/32701962 http://dx.doi.org/10.1371/journal.pone.0233252 |
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