Prioritizing potential ACE2 inhibitors in the COVID-19 pandemic: Insights from a molecular mechanics-assisted structure-based virtual screening experiment

Angiotensin-converting enzyme 2 (ACE2) is a membrane-bound zinc metallopeptidase that generates the vasodilatory peptide angiotensin 1–7 and thus performs a protective role in heart disease. It is considered an important therapeutic target in controlling the COVID-19 outbreak, since SARS-CoV-2 enter...

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Detalles Bibliográficos
Autores principales: Teralı, Kerem, Baddal, Buket, Gülcan, Hayrettin Ozan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377801/
https://www.ncbi.nlm.nih.gov/pubmed/32739642
http://dx.doi.org/10.1016/j.jmgm.2020.107697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377801/
https://www.ncbi.nlm.nih.gov/pubmed/32739642
http://dx.doi.org/10.1016/j.jmgm.2020.107697

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