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Nrf2 inhibits ferroptosis and protects against acute lung injury due to intestinal ischemia reperfusion via regulating SLC7A11 and HO-1

Acute lung injury (ALI) is a syndrome associated with a high mortality rate. Nrf2 is a key regulator of intracellular oxidation homeostasis that plays a pivotal role in controlling lipid peroxidation, which is closely related to the process of ferroptosis. However, the intrinsic effect of Nrf2 on fe...

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Detalles Bibliográficos
Autores principales: Dong, Hui, Qiang, Zhuanzhuan, Chai, Dongdong, Peng, Jiali, Xia, Yangyang, Hu, Rong, Jiang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377827/
https://www.ncbi.nlm.nih.gov/pubmed/32601262
http://dx.doi.org/10.18632/aging.103378