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Melatonin protects against apoptosis of megakaryocytic cells via its receptors and the AKT/mitochondrial/caspase pathway

Clinical studies have shown that melatonin lowers the frequency of thrombocytopenia in patients with cancer undergoing radiotherapy or chemotherapy. Here, we investigated the mechanisms by which melatonin promotes platelet formation and survival. Our results show that melatonin exerted protective ef...

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Detalles Bibliográficos
Autores principales: Yang, Mo, Li, Liang, Chen, Shichao, Li, Suyi, Wang, Bo, Zhang, Changhua, Chen, Youpeng, Yang, Liuming, Xin, Hongwu, Chen, Chun, Xu, Xiaojun, Zhang, Qing, He, Yulong, Ye, Jieyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377846/
https://www.ncbi.nlm.nih.gov/pubmed/32651992
http://dx.doi.org/10.18632/aging.103483