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Silencing of long non-coding RNA Sox2ot inhibits oxidative stress and inflammation of vascular smooth muscle cells in abdominal aortic aneurysm via microRNA-145-mediated Egr1 inhibition

Long non-coding RNAs (lncRNAs) have been largely reported to contribute to the development and progression of abdominal aortic aneurysm (AAA), a common vascular degenerative disease. The present study was set out with the aim to investigate the possible role of lncRNA Sox2ot in the development of AA...

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Detalles Bibliográficos
Autores principales: Lin, Huyu, You, Bin, Lin, Xiandong, Wang, Xiaohu, Zhou, Dongsheng, Chen, Zhiqun, Chen, Yuanxiang, Wang, Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377859/
https://www.ncbi.nlm.nih.gov/pubmed/32629426
http://dx.doi.org/10.18632/aging.103077