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The YAP/SERCA2a signaling pathway protects cardiomyocytes against reperfusion-induced apoptosis

Mitochondria and the endoplasmic reticulum (ER) are known to promote cardiac ischemia/reperfusion (I/R) injury. Overexpression of yes-associated protein (YAP) and/or sarcoplasmic reticulum calcium ATPase 2a (SERCA2a) has been shown to protect cardiomyocytes against I/R-induced injury. Here, we show...

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Detalles Bibliográficos
Autores principales: Zhong, Jiankai, Ouyang, Haichun, Zheng, Sulin, Guo, Zhongzhou, Chen, Yuying, Zhong, Yuanlin, Zhong, Wenhao, Zuo, Liuer, Lu, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377864/
https://www.ncbi.nlm.nih.gov/pubmed/32645692
http://dx.doi.org/10.18632/aging.103481