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The YAP/SERCA2a signaling pathway protects cardiomyocytes against reperfusion-induced apoptosis
Mitochondria and the endoplasmic reticulum (ER) are known to promote cardiac ischemia/reperfusion (I/R) injury. Overexpression of yes-associated protein (YAP) and/or sarcoplasmic reticulum calcium ATPase 2a (SERCA2a) has been shown to protect cardiomyocytes against I/R-induced injury. Here, we show...
Autores principales: | Zhong, Jiankai, Ouyang, Haichun, Zheng, Sulin, Guo, Zhongzhou, Chen, Yuying, Zhong, Yuanlin, Zhong, Wenhao, Zuo, Liuer, Lu, Jianhua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377864/ https://www.ncbi.nlm.nih.gov/pubmed/32645692 http://dx.doi.org/10.18632/aging.103481 |
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