Loss of β-catenin via activated GSK3β causes diabetic retinal neurodegeneration by instigating a vicious cycle of oxidative stress-driven mitochondrial impairment

Synaptic neurodegeneration of retinal ganglion cells (RGCs) is the earliest event in the pathogenesis of diabetic retinopathy. Our previous study proposed that impairment of mitochondrial trafficking by hyperphosphorylated tau is a potential contributor to RGCs synapse degeneration. However, other m...

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Detalles Bibliográficos
Autores principales: Shu, Xing-Sheng, Zhu, Huazhang, Huang, Xiaoyan, Yang, Yangfan, Wang, Dandan, Zhang, Yiling, Zhang, Weizhen, Ying, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377872/
https://www.ncbi.nlm.nih.gov/pubmed/32575075
http://dx.doi.org/10.18632/aging.103446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377872/
https://www.ncbi.nlm.nih.gov/pubmed/32575075
http://dx.doi.org/10.18632/aging.103446

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