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Lack of retinoid acid receptor-related orphan receptor alpha accelerates and melatonin supplementation prevents testicular aging

The role of retinoid acid receptor-related orphan receptor alpha (RORα) on male reproductive functions during aging is unclear. Here, we analyze the morphological changes in the testis of both young and aged RORα-deficient mice, with and without melatonin supplementation. Young mutants showed vacuol...

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Detalles Bibliográficos
Autores principales: Sayed, Ramy K. A., Mokhtar, Doaa M., Fernández-Ortiz, Marisol, Fernández-Martínez, José, Aranda-Martínez, Paula, Escames, Germaine, Acuña-Castroviejo, Darío
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377884/
https://www.ncbi.nlm.nih.gov/pubmed/32644943
http://dx.doi.org/10.18632/aging.103654