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CAMKIIγ is a targetable driver of multiple myeloma through CaMKIIγ/ Stat3 axis

Aberrant activation of CAMKIIγ has been linked to leukemia and T-cell lymphoma, but not multiple myeloma (MM). The purpose of this study was to explore the role of CaMKIIγ in the pathogenesis and therapy of MM. In this study, we found that CaMKIIγ was aberrantly activated in human MM and its express...

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Detalles Bibliográficos
Autores principales: Yang, Linlin, Wu, Bowen, Wu, Zhaoxing, Xu, Ying, Wang, Ping, Li, Mengyuan, Xu, Rongzhen, Liang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377902/
https://www.ncbi.nlm.nih.gov/pubmed/32658867
http://dx.doi.org/10.18632/aging.103490