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Urinary Cell Transcriptome Profiling and Identification of ITM2A, SLAMF6, and IKZF3 as Biomarkers of Acute Rejection in Human Kidney Allografts

Identification of a shared gene expression pattern between T cell–mediated rejection (TCMR) and antibody-mediated rejection (AMR) in human kidney allografts may help prioritize targets for the treatment of both types of acute rejection. METHODS. We performed RNA sequencing and bioinformatics of geno...

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Detalles Bibliográficos
Autores principales: Dooley, Bryan J., Verma, Akanksha, Ding, Ruchuang, Yang, Hua, Muthukumar, Thangamani, Lubetzky, Michele, Shankaranarayanan, Divya, Elemento, Olivier, Suthanthiran, Manikkam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377920/
https://www.ncbi.nlm.nih.gov/pubmed/32766436
http://dx.doi.org/10.1097/TXD.0000000000001035