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Profiling cytotoxic microRNAs in pediatric and adult glioblastoma cells by high-content screening, identification, and validation of miR-1300

MicroRNAs play an important role in the regulation of mRNA translation and have therapeutic potential in cancer and other diseases. To profile the landscape of microRNAs with significant cytotoxicity in the context of glioblastoma (GBM), we performed a high-throughput screen in adult and pediatric G...

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Detalles Bibliográficos
Autores principales: Boissinot, M., King, H., Adams, M., Higgins, J., Shaw, G., Ward, T. A., Steele, L. P., Tams, D., Morton, R., Polson, E., da Silva, B., Droop, A., Hayes, J. L., Martin, H., Laslo, P., Morrison, E., Tomlinson, D. C., Wurdak, H., Bond, J., Lawler, S. E., Short, S. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378045/
https://www.ncbi.nlm.nih.gov/pubmed/32555332
http://dx.doi.org/10.1038/s41388-020-1360-y