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Trajectory analysis quantifies transcriptional plasticity during macrophage polarization

In recent years, macrophages have been shown to be tremendously plastic in both in vitro and in vivo settings; however, it remains unclear whether macrophages retain any persistent memory of past polarization states which may then impact their future repolarization to new states. Here, we perform de...

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Detalles Bibliográficos
Autores principales: Liu, Serena X., Gustafson, Heather H., Jackson, Dana L., Pun, Suzie H., Trapnell, Cole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378057/
https://www.ncbi.nlm.nih.gov/pubmed/32703960
http://dx.doi.org/10.1038/s41598-020-68766-w