High uptake of (68)Ga-PSMA and (18)F-DCFPyL in the peritumoral area of rat gliomas due to activated astrocytes

BACKGROUND: Recent studies reported on high uptake of the PSMA ligands [(68)Ga]HBED-CC ((68)Ga-PSMA) and (18)F-DCFPyL in cerebral gliomas. This study explores the regional uptake and cellular targets of (68)Ga-PSMA and (18)F-DCFPyL in three different rat glioma models. METHODS: F98, 9 L, or U87 rat...

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Detalles Bibliográficos
Autores principales: Oliveira, Dennis, Stegmayr, Carina, Heinzel, Alexander, Ermert, Johannes, Neumaier, Bernd, Shah, N. Jon, Mottaghy, Felix M., Langen, Karl-Josef, Willuweit, Antje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378136/
https://www.ncbi.nlm.nih.gov/pubmed/32451793
http://dx.doi.org/10.1186/s13550-020-00642-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378136/
https://www.ncbi.nlm.nih.gov/pubmed/32451793
http://dx.doi.org/10.1186/s13550-020-00642-0

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