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Zeta Inhibitory Peptide attenuates learning and memory by inducing NO-mediated downregulation of AMPA receptors
Zeta inhibitory peptide (ZIP), a PKMζ inhibitor, is widely used to interfere with the maintenance of acquired memories. ZIP is able to erase memory even in the absence of PKMζ, via an unknown mechanism. We found that ZIP induces redistribution of the AMPARGluA1 in HEK293 cells and primary cortical n...
Autores principales: | Bingor, Alexey, Haham, Tomer, Thornton, Claire, Stern-Bach, Yael, Yaka, Rami |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378180/ https://www.ncbi.nlm.nih.gov/pubmed/32703948 http://dx.doi.org/10.1038/s41467-020-17484-y |
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