Phosphate-dependent aggregation of [KL](n) peptides affects their membranolytic activity

In this study, we investigate how the length of amphiphilic β-sheet forming peptides affects their interaction with membranes. Four polycationic model peptides with lengths from 6 to 18 amino acids were constructed from simple Lys-Leu repeats, giving [KL](n=3,5,7,9). We found that (1) they exhibit a...

Descripción completa

Detalles Bibliográficos
Autores principales: Strandberg, Erik, Schweigardt, Fabian, Wadhwani, Parvesh, Bürck, Jochen, Reichert, Johannes, Cravo, Haroldo L. P., Burger, Luisa, Ulrich, Anne S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378186/
https://www.ncbi.nlm.nih.gov/pubmed/32704013
http://dx.doi.org/10.1038/s41598-020-69162-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378186/
https://www.ncbi.nlm.nih.gov/pubmed/32704013
http://dx.doi.org/10.1038/s41598-020-69162-0

Ejemplares similares