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Phosphate-dependent aggregation of [KL](n) peptides affects their membranolytic activity
In this study, we investigate how the length of amphiphilic β-sheet forming peptides affects their interaction with membranes. Four polycationic model peptides with lengths from 6 to 18 amino acids were constructed from simple Lys-Leu repeats, giving [KL](n=3,5,7,9). We found that (1) they exhibit a...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378186/ https://www.ncbi.nlm.nih.gov/pubmed/32704013 http://dx.doi.org/10.1038/s41598-020-69162-0 |