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Regulation of MYO18B mRNA by a network of C19MC miRNA-520G, IFN-γ, CEBPB, p53 and bFGF in hepatocellular carcinoma

MYO18B has been proposed to contribute to the progression of hepatocellular carcinoma (HCC). However, the signals that govern MYO18B transcription are not known. Here we show that, a network of C19MC miRNA-520G, IFN-γ, CEBPB and p53 transcriptional-defects promote MYO18B mRNA expression in HCCs. IFN...

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Detalles Bibliográficos
Autores principales: Jinesh, Goodwin G., Napoli, Marco, Ackerman, Hayley D., Raulji, Payal M., Montey, Nicole, Flores, Elsa R., Brohl, Andrew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378193/
https://www.ncbi.nlm.nih.gov/pubmed/32704163
http://dx.doi.org/10.1038/s41598-020-69179-5