Photoactivatable oncolytic adenovirus for optogenetic cancer therapy

Virotherapy using oncolytic adenovirus is an effective anticancer strategy. However, the tumor selectivity of oncolytic adenoviruses is not enough high. To develop oncolytic adenovirus with a low risk of off-tumor toxicity, we constructed a photoactivatable oncolytic adenovirus (paOAd). In response...

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Detalles Bibliográficos
Autores principales: Hagihara, Yasuko, Sakamoto, Ayaka, Tokuda, Takashi, Yamashita, Tomoki, Ikemoto, Sena, Kimura, Ayaka, Haruta, Makito, Sasagawa, Kiyotaka, Ohta, Jun, Takayama, Kazuo, Mizuguchi, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378209/
https://www.ncbi.nlm.nih.gov/pubmed/32703933
http://dx.doi.org/10.1038/s41419-020-02782-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378209/
https://www.ncbi.nlm.nih.gov/pubmed/32703933
http://dx.doi.org/10.1038/s41419-020-02782-6

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