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Photoactivatable oncolytic adenovirus for optogenetic cancer therapy
Virotherapy using oncolytic adenovirus is an effective anticancer strategy. However, the tumor selectivity of oncolytic adenoviruses is not enough high. To develop oncolytic adenovirus with a low risk of off-tumor toxicity, we constructed a photoactivatable oncolytic adenovirus (paOAd). In response...
Autores principales: | Hagihara, Yasuko, Sakamoto, Ayaka, Tokuda, Takashi, Yamashita, Tomoki, Ikemoto, Sena, Kimura, Ayaka, Haruta, Makito, Sasagawa, Kiyotaka, Ohta, Jun, Takayama, Kazuo, Mizuguchi, Hiroyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378209/ https://www.ncbi.nlm.nih.gov/pubmed/32703933 http://dx.doi.org/10.1038/s41419-020-02782-6 |
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