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Transcriptome analysis of desmoplastic small round cell tumors identifies actionable therapeutic targets: a report from the Children’s Oncology Group

To further understand the molecular pathogenesis of desmoplastic small round cell tumor (DSRCT), a fatal malignancy occurring primarily in adolescent/young adult males, we used next-generation RNA sequencing to investigate the gene expression profiles intrinsic to this disease. RNA from DSRCT specim...

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Detalles Bibliográficos
Autores principales: Hingorani, Pooja, Dinu, Valentin, Zhang, Xiyuan, Lei, Haiyan, Shern, Jack F., Park, Jin, Steel, Jason, Rauf, Femina, Parham, David, Gastier-Foster, Julie, Hall, David, Hawkins, Douglas S., Skapek, Stephen X., Labaer, Joshua, McEachron, Troy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378211/
https://www.ncbi.nlm.nih.gov/pubmed/32703985
http://dx.doi.org/10.1038/s41598-020-69015-w