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Intrinsic transcriptomic sex differences in human endothelial cells at birth and in adults are associated with coronary artery disease targets

Sex differences in endothelial cell (EC) biology may reflect intrinsic differences driven by chromosomes or sex steroid exposure and gender differences accumulated over life. We analysed EC gene expression data from boy–girl twins at birth and in non-twin adults to detect sex differences at differen...

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Detalles Bibliográficos
Autores principales: Hartman, Robin J. G., Kapteijn, Daniek M. C., Haitjema, Saskia, Bekker, Mireille N., Mokry, Michal, Pasterkamp, Gerard, Civelek, Mete, den Ruijter, Hester M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378217/
https://www.ncbi.nlm.nih.gov/pubmed/32704153
http://dx.doi.org/10.1038/s41598-020-69451-8