Cargando…
DNA unchained: two assays to discover and study inhibitors of the DNA clustering function of barrier-to-autointegration factor
The protein barrier-to-autointegration factor (BAF) and its interaction partners, the LEM (LAP2B, emerin, MAN1)-domain proteins, constitute a powerful cytoplasmic DNA defense mechanism. Invading DNA molecules are quickly bound by the BAF system and trapped in membrane compartments. This decreases th...
Autores principales: | Burger, Michael, Schmitt-Koopmann, Caroline, Leroux, Jean-Christophe |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378220/ https://www.ncbi.nlm.nih.gov/pubmed/32704141 http://dx.doi.org/10.1038/s41598-020-69246-x |
Ejemplares similares
-
Disorders of ubiquitylation: unchained inflammation
por: Beck, David B., et al.
Publicado: (2022) -
Repair of nuclear ruptures requires barrier-to-autointegration factor
por: Halfmann, Charles T., et al.
Publicado: (2019) -
The SET Complex Acts as a Barrier to Autointegration of HIV-1
por: Yan, Nan, et al.
Publicado: (2009) -
Barrier-to-Autointegration Factor Proteome Reveals Chromatin-Regulatory Partners
por: Montes de Oca, Rocío, et al.
Publicado: (2009) -
Barrier-to-autointegration factor: major roles in chromatin decondensation and nuclear assembly
por: Segura-Totten, Miriam, et al.
Publicado: (2002)