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Cardioprotective effects of miR-34a silencing in a rat model of doxorubicin toxicity

Cardiotoxicity remains a serious problem in anthracycline-treated oncologic patients. Therapeutic modulation of microRNA expression is emerging as a cardioprotective approach in several cardiovascular pathologies. MiR-34a increased in animals and patients exposed to anthracyclines and is involved in...

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Detalles Bibliográficos
Autores principales: Piegari, Elena, Cozzolino, Anna, Ciuffreda, Loreta Pia, Cappetta, Donato, De Angelis, Antonella, Urbanek, Konrad, Rossi, Francesco, Berrino, Liberato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378226/
https://www.ncbi.nlm.nih.gov/pubmed/32704131
http://dx.doi.org/10.1038/s41598-020-69038-3