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Der p 1-based immunotoxin as potential tool for the treatment of dust mite respiratory allergy

Immunotoxins appear as promising therapeutic molecules, alternative to allergen-specific-immunotherapy. In this work, we achieved the development of a protein chimera able to promote specific cell death on effector cells involved in the allergic reaction. Der p 1 allergen was chosen as cell-targetin...

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Detalles Bibliográficos
Autores principales: Lázaro-Gorines, Rodrigo, López-Rodríguez, Juan Carlos, Benedé, Sara, González, Miguel, Mayorga, Cristobalina, Vogel, Lothar, Martínez-del-Pozo, Álvaro, Lacadena, Javier, Villalba, Mayte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378242/
https://www.ncbi.nlm.nih.gov/pubmed/32703972
http://dx.doi.org/10.1038/s41598-020-69166-w