Cargando…

Photodynamic exposure of Rose-Bengal inhibits Tau aggregation and modulates cytoskeletal network in neuronal cells

The intracellular Tau aggregates are known to be associated with Alzheimer’s disease. The inhibition of Tau aggregation is an important strategy for screening of therapeutic molecules in Alzheimer's disease. Several classes of dyes possess a unique property of photo-excitation, which is applied...

Descripción completa

Detalles Bibliográficos
Autores principales: Dubey, Tushar, Gorantla, Nalini Vijay, Chandrashekara, Kagepura Thammaiah, Chinnathambi, Subashchandrabose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378248/
https://www.ncbi.nlm.nih.gov/pubmed/32704015
http://dx.doi.org/10.1038/s41598-020-69403-2