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Enhancement of O-linked N-acetylglucosamine modification promotes metastasis in patients with colorectal cancer and concurrent type 2 diabetes mellitus

Reversible post-translational modification of serine and threonine residues by O-linked N-acetylglucosamine (O-GlcNAc), termed O-GlcNAcylation has been indicated to regulate the activities of a number of different proteins. Augmented O-GlcNAcylation contributes to the etiologies of type 2 diabetes m...

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Detalles Bibliográficos
Autores principales: Naka, Yutaka, Okada, Toshihiko, Nakagawa, Takatoshi, Kobayashi, Eiko, Kawasaki, Yuka, Tanaka, Yasuyoshi, Tawa, Hideki, Hirata, Yuki, Kawakami, Ken, Kakimoto, Kazuki, Inoue, Takuya, Takeuchi, Toshihisa, Fukunishi, Shinya, Hirose, Yoshinobu, Uchiyama, Kazuhisa, Asahi, Michio, Higuchi, Kazuhide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378307/
https://www.ncbi.nlm.nih.gov/pubmed/32724357
http://dx.doi.org/10.3892/ol.2020.11665