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MEF2C and HDAC5 regulate Egr1 and Arc genes to increase dendritic spine density and complexity in early enriched environment

We investigated the effects of environmental enrichment during critical period of early postnatal life and how it interplays with the epigenome to affect experience-dependent visual cortical plasticity. Mice raised in an EE from birth to during CP have increased spine density and dendritic complexit...

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Detalles Bibliográficos
Autores principales: Puang, Shu Juan, Elanggovan, Bavani, Ching, Tendy, Sng, Judy C.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378308/
https://www.ncbi.nlm.nih.gov/pubmed/32714604
http://dx.doi.org/10.1042/NS20190147