Insulin and Metformin Control Cell Proliferation by Regulating TDG-Mediated DNA Demethylation in Liver and Breast Cancer Cells

Type 2 diabetes mellitus (T2DM) is a frequent comorbidity of cancer. Hyperinsulinemia secondary to T2DM promotes cancer progression, whereas antidiabetic agents, such as metformin, have anticancer effects. However, the detailed mechanism for insulin and metformin-regulated cancer cell proliferation...

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Detalles Bibliográficos
Autores principales: Yan, Jia-Bao, Lai, Chien-Cheng, Jhu, Jin-Wei, Gongol, Brendan, Marin, Traci L., Lin, Shih-Chieh, Chiu, Hsiang-Yi, Yen, Chia-Jui, Wang, Liang-Yi, Peng, I-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378318/
https://www.ncbi.nlm.nih.gov/pubmed/32728616
http://dx.doi.org/10.1016/j.omto.2020.06.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378318/
https://www.ncbi.nlm.nih.gov/pubmed/32728616
http://dx.doi.org/10.1016/j.omto.2020.06.010

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