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Adrenomedullin has a cytoprotective role against endoplasmic reticulum stress for pancreatic β‐cells in autocrine and paracrine manners

AIMS/INTRODUCTION: Pancreatic β‐cells are sensitive to endoplasmic reticulum (ER) stress, which has a major role in the context of β‐cell death. Adrenomedullin (ADM) has been shown to exert a cytoprotective effect under various pathophysiological conditions. Several studies have suggested that thiaz...

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Detalles Bibliográficos
Autores principales: Suetomi, Risa, Ohta, Yasuharu, Akiyama, Masaru, Matsumura, Takuro, Taguchi, Akihiko, Yamamoto, Kaoru, Kamatani, Takashi, Tanizawa, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378419/
https://www.ncbi.nlm.nih.gov/pubmed/31989791
http://dx.doi.org/10.1111/jdi.13218