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IgG Subclass Determines Suppression Versus Enhancement of Humoral Alloimmunity to Kell RBC Antigens in Mice

It has long been appreciated that immunoglobulins are not just the effector endpoint of humoral immunity, but rather have a complex role in regulating antibody responses themselves. Donor derived anti-RhD IgG has been used for over 50 years as an immunoprophylactic to prevent maternal alloimmunizati...

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Detalles Bibliográficos
Autores principales: Shinde, Paurvi, Howie, Heather L., Stegmann, Tamara C., Hay, Ariel M., Waterman, Hayley R., Szittner, Zoltan, Bentlage, Arthur E. H., Kapp, Linda, Lissenberg-Thunnissen, Suzanne N., Dekkers, Gillian, Schasfoort, Richard B. M., Ratcliffe, Sarah J., Smolkin, Mark E., Vidarsson, Gestur, van der Schoot, C. Ellen, Hudson, Krystalyn E., Zimring, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378678/
https://www.ncbi.nlm.nih.gov/pubmed/32765523
http://dx.doi.org/10.3389/fimmu.2020.01516