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Cranial irradiation at early postnatal age impairs stroke-induced neural stem/progenitor cell response in the adult brain

Cranial irradiation (IR) is commonly used to treat primary brain tumors and metastatic diseases. However, cranial IR-treated patients often develop vascular abnormalities later in life that increase their risk for cerebral ischemia. Studies in rodents have demonstrated that IR impairs maintenance of...

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Detalles Bibliográficos
Autores principales: Neumann, Susanne, Porritt, Michelle J., Osman, Ahmed M., Kuhn, H. Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378832/
https://www.ncbi.nlm.nih.gov/pubmed/32703986
http://dx.doi.org/10.1038/s41598-020-69266-7