Anti-malarial Drugs Reduce Vascular Smooth Muscle Cell Proliferation via Activation of AMPK and Inhibition of Smad3 Signaling

OBJECTIVE: The aim of this study was to investigate the effects of 2 anti-malarial drugs, chloroquine (CQ) and hydroxychloroquine (HCQ), on inhibition of vascular smooth muscle cell (VSMC) proliferation both in vivo and in vitro via Adenosine monophosphate-activated protein kinase (AMPK) activation....

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Heejung, Han, Jung-Hwa, Kim, Sujin, Kim, Suji, Cho, Du-Hyong, Woo, Chang-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Lipidology and Atherosclerosis 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379117/
https://www.ncbi.nlm.nih.gov/pubmed/32821717
http://dx.doi.org/10.12997/jla.2019.8.2.267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379117/
https://www.ncbi.nlm.nih.gov/pubmed/32821717
http://dx.doi.org/10.12997/jla.2019.8.2.267

Ejemplares similares