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Anti-malarial Drugs Reduce Vascular Smooth Muscle Cell Proliferation via Activation of AMPK and Inhibition of Smad3 Signaling
OBJECTIVE: The aim of this study was to investigate the effects of 2 anti-malarial drugs, chloroquine (CQ) and hydroxychloroquine (HCQ), on inhibition of vascular smooth muscle cell (VSMC) proliferation both in vivo and in vitro via Adenosine monophosphate-activated protein kinase (AMPK) activation....
Autores principales: | Lee, Heejung, Han, Jung-Hwa, Kim, Sujin, Kim, Suji, Cho, Du-Hyong, Woo, Chang-Hoon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society of Lipidology and Atherosclerosis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379117/ https://www.ncbi.nlm.nih.gov/pubmed/32821717 http://dx.doi.org/10.12997/jla.2019.8.2.267 |
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